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Clinical and laboratory-instrumental features of pneumonia caused by Mycoplasma pneumoniae in childhood

https://doi.org/10.31146/2949-4664-apps-2-2-65-68

Abstract

Mycoplasma pneumoniae is the most common causative agent of bacterial pneumonia among school-age children. The study analyzed the clinical cases of 460 children hospitalized with radiologically confirmed pneumonia in the period from 2022 to 2023. Pneumonia caused by Mycoplasma pneumoniae was detected in 198 patients. The diagnosis was confirmed by ELISA diagnostics and PCR diagnostics. Clinically, pneumonia of this pathogen proceeded without complications, did not require treatment in intensive care and intensive care. Mycoplasma pneumoniae is most often observed among preschool and school-age children. In this regard, an examination for Mycoplasma pneumoniae should be carried out in preschool and school-age children to identify the pathogen and timely prescribe antibacterial therapy.

About the Authors

P. V. Berezhanskij
Sechenov Moscow Medical University; Morozov Children’s Clinical Hospital; Reasearch Clinical Institute of Childhood of the Ministry of Health of the Moscow Region; Peoples’ Friendship University of Russia named after Patrice Lumumba
Russian Federation


T. A. Gutyrchik
Morozov Children’s Clinical Hospital
Russian Federation


I. A. Antonyan
Morozov Children’s Clinical Hospital; N.I. Pirogov Russian National Research Medical University
Russian Federation


A. B. Malakhov
Sechenov Moscow Medical University; Morozov Children’s Clinical Hospital; Reasearch Clinical Institute of Childhood of the Ministry of Health of the Moscow Region
Russian Federation


Sh. A. Gitinov
Morozov Children’s Clinical Hospital; Peoples’ Friendship University of Russia named after Patrice Lumumba
Russian Federation


References

1. Meyer Sauteur P. M., Beeton M. L.; ESGMAC the ESGMAC MAPS study group. Mycoplasma pneumoniae: gone forever? Lancet Microbe. 2023 Oct;4(10): e763. doi: 10.1016/S2666-5247(23)00182-9.

2. Daxboeck F., Blacky A., Seidl R., Krause R., Assadian O. Diagnosis, treatment, and prognosis of Mycoplasma pneumoniae childhood encephalitis: systematic review of 58 cases. Journal of Child Neurology. 2004 Nov;19(11):865-71. doi: 10.1177/08830738040190110401.

3. Meyer Sauteur P. M., Streuli J. C., Iff T., Goetschel P. Mycoplasma pneumoniae-associated encephalitis in childhood-nervous system disorder during or after arespiratory tract infection. Klinische Padiatrie. 2011 Jul;223(4):209-13. doi: 10.1055/s-0031-1271717.

4. Meyer Sauteur P. M., Goetschel P., Lautenschlager S. Mycoplasma pneumoniae and mucositis - part of the Stevens-Johnson syndrome spectrum. Journal der Deutschen Dermatologischen Gesellschaft. 2012 Oct;10(10):740-6. doi: 10.1111/j.1610-0387.2012.07951.x.

5. Geppe N.A. [Acute respiratory tract infections in children. Diagnosis, treatment, prevention: clinical guidelines]. 3rd edition. Moscow. MedKom-Pro Publ., 2023, 348 p. (in Russ.) @@ Геппе Н. А. Острые инфекции дыхательных путей удетей. Диагностика, лечение, профилактика: клиническое руководство. 3-е издание, обновленное - М.: МедКом-Про, 2023.- 348с.

6. Geppe N.A. [Community-acquired pneumonia in children. Clinical Guide]. Moscow. MedKom-Pro Publ., 2020, 80p.(in Russ.)@@ Геппе Н. А. Внебольничная пневмония удетей. Клиническое руководство. М.: МедКом-Про, 2020. 80с.

7. Musher D.M., Thorner A. R. Community-acquired pneumonia. The New England Journal of Medicine. 2014 Oct 23;371(17):1619-28. doi: 10.1056/NEJMra1312885.

8. Harper S.A., Bradley J. S., Englund J. A., File T. M., Gravenstein S., Hayden F. G., McGeer A.J., Neuzil K. M., Pavia A. T., Tapper M. L., Uyeki T. M., Zimmerman R. K.; Expert Panel of the Infectious Diseases Society of America. Seasonal influenza in adults and children - diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis. 2009 Apr 15;48(8):1003-32. doi: 10.1086/598513.

9. Li X., Atkinson T. P., Hagood J., Makris C., Duffy L. B., Waites K. B. Emerging macrolide resistance in Mycoplasma pneumoniae in children: detection and characterization of resistant isolates. The Pediatric Infectious Disease Journal. 2009 Aug 28(8):693-6. doi: 10.1097/INF.0b013e31819e3f7a.

10. Yamada M., Buller R., Bledsoe S., Storch G. A. Rising rates of macrolide-resistant Mycoplasma pneumoniae in the central United States. The Pediatric Infectious Disease Journal. 2012 Apr;31(4):409-0. doi: 10.1097/INF.0b013e318247f3e0.

11. Critchley I.A., Jones M. E., Heinze P. D. et al. In vitro activity of levofloxacin against contemporary clinical isolates of Legionella pneumophila, Mycoplasma pneumoniae and Chlamydia pneumoniae from North America and Europe. Clinical Microbiology and Infection. 2002 Apr;8(4):214-21. doi: 10.1046/j.1469-0691.2002.00392.x.


Review

For citations:


Berezhanskij P.V., Gutyrchik T.A., Antonyan I.A., Malakhov A.B., Gitinov Sh.A. Clinical and laboratory-instrumental features of pneumonia caused by Mycoplasma pneumoniae in childhood. Archives of Pediatrics and Pediatric Surgery. 2024;2(2):65-68. (In Russ.) https://doi.org/10.31146/2949-4664-apps-2-2-65-68

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ISSN 2949-4664 (Print)