Stress in childhood: clinical implications and therapeutic strategies
https://doi.org/10.31146/2949-4664-apps-2-1-182-195
Abstract
Stress is a universal evolutionarily determined physiological mechanism that allows to mobilize of organism reserves in life-threatening situations. However, like any mobilisation process, it is possible only for a short period of time. Then, the reserves are depleted and, according to Hans Sellier’s theory, distress occurs. In the context of the human organism, in our case, the child’s organism, stress-induced pathology debuts, which often has a systemic character, affecting many organs and systems. In addition, stress, acting as an epigenetic factor, can provoke the debut of diseases to which a particular individual has a predisposition. The literature review presents the modern concept of stress, its influence on the growing organism of a child and describes a number of stress-associated pathological conditions.
About the Authors
E. V. Shreiner
Novosibirsk State University; Institute of chemical, Institute of Chemical Biology and Fundamental Medicine of the SB RAS
Russian Federation
Russian Federation
E. A. Balakireva
Belgorod State Research University
Russian Federation
Russian Federation
V. I. Bystrova
Novosibirsk State University
Russian Federation
Russian Federation
A. Ya. Kovaleva
Institute of chemical, Institute of Chemical Biology and Fundamental Medicine of the SB RAS
Russian Federation
Russian Federation
A. I. Khavkin
Belgorod State Research University; Research Clinical Institute of Childhood, Ministry of Health of the Moscow Region
Russian Federation
Russian Federation
References
1. Akarachkova E. S., Blinov D. V., Klimov L. V., Kotova O. V., Tsareva E. V. Stress and stress-associated disorders in children. Meditsinskiy sovet = Medical Council. 2023;(12):210-220. (In Russ.) doi: 10.21518/ms2022-016.@@ Акарачкова Е. С., Блинов Д. В., Климов Л. В., Котова О. В., Царева Е. В. Стресс и стресс-связанные расстройства у детей. Медицинский Совет. 2023;(12):210-220. doi: 10.21518/ms2022-016.
2. Palanichamy T., Sharma M. K., Sahu M., Kanchana D. M. Influence of Esports on stress: A systematic review. Ind Psychiatry J. 2020 Jul-Dec;29(2):191-199. doi: 10.4103/ipj.ipj_195_20.
3. Gałecki P., Talarowska M. Inflammatory theory of depression. Psychiatr Pol. 2018 Jun 30;52(3):437-447. English, Polish. doi: 10.12740/PP/76863.
4. Stress in children and adolescents: causes and consequences, treatment and prevention. Clinical manual / Edd Akarachkova E. S. St. Petersburg: Scythia-print; Moscow.: Profmedpress, 2022. 90 p. (in Russ.)@@ Cтресс у детей и подростков: причины и последствия, лечение и профилактика. Клиническое руководство / Акарачкова Е. С. и др. - СПб.: Скифия-принт; М.: Профмедпресс, 2022. - 90 с. ISBN 978-5-98620-587-8
5. Komarova О.N., Khavkin A. I. Correlation Between Stress, Immunity and Intestinal Microbiota. Pediatric pharmacology. 2020;17(1):18-24. (In Russ.) doi: 10.15690/pf.v17i1.2078.@@ Комарова О. Н., Хавкин А. И. Взаимосвязь стресса, иммунитета и кишечной микробиоты. Педиатрическая фармакология. 2020; 17 (1): 18-24. doi: 10.15690/pf.v17i1.2078.
6. Scaramella F., Quaranta M. Influenza del tessuto adenoideo ipertrofico sulle strutture maxillo-facciali [Effect of hypertrophic adenoid tissue on maxillofacial structures]. Dent Cadmos. 1984 May;52(5 Suppl):37-50.
7. Shah S.S., Nankar M. Y., Bendgude V. D., Shetty B. R. Orofacial Myofunctional Therapy in Tongue Thrust Habit: A Narrative Review.Int J Clin Pediatr Dent. 2021 Mar-Apr;14(2):298-303. doi: 10.5005/jp-journals-10005-1926.
8. Yamanishi K., Doe N., Mukai K. et al. Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice. Transl Psychiatry. 2022 Sep 23;12(1):404. doi: 10.1038/s41398-022-02175-7.
9. Kulikov A.G., Zaytseva T. N., Pyzhevskaya O. P., Ivanova E. R. Scoliosis in children: new approaches to the solution of important medical and social problems. Mediko-sotsyl’naya ekspertiza i reabilitatsiya (Medical and Social Expert Evaluation and Rehabilitation, Russian Journal). 2016; 19 (4): 178-181. (In Russ.). doi: 10.18821/1560-9537-2016-19-4-178-181.@@ Куликов А. Г., Зайцева Т. Н., Пыжевская О. П., Иванова Е. Р. Сколиоз у детей: новые подходы к решению важной медико-социальной проблемы. Медико-социальная экспертиза и реабилитация. 2016; 19(4): 178-181. doi: 10.18821/1560-9537-2016-19-4-178-181.
10. Shorey S., Ng E. D., Wong CH.J. Global prevalence of depression and elevated depressive symptoms among adolescents: A systematic review and meta-analysis. Br J Clin Psychol. 2022 Jun;61(2):287-305. doi: 10.1111/bjc.12333.
11. Plener P.L., Kaess M., Schmahl C., Pollak S., Fegert J. M., Brown R. C. Nonsuicidal Self-Injury in Adolescents. Dtsch Arztebl Int. 2018 Jan 19;115(3):23-30. doi: 10.3238/arztebl.2018.0023.
12. Khan A.N., Jaffee S. R. Alexithymia in individuals maltreated as children and adolescents: a meta-analysis. J Child Psychol Psychiatry. 2022 Sep;63(9):963-972. doi: 10.1111/jcpp.13616.
13. Akimov A. M. Parameters of stressful events at a young age (data of cross-sectional epidemiological studies).Russian Journal of Cardiology. 2020;25(6):3660. (In Russ.) doi:10.15829/1560-4071-2020-3660.@@ Акимов А. М. Параметры основных стрессовых событий в молодом возрасте по данным кросс-секционных эпидемиологических исследований. Российский кардиологический журнал. 2020;25(6):3660. doi:10.15829/1560-4071-2020-3660.
14. Khavkin A. I., Fayzullina R. A., Belmer S. V. et al. Diagnosis and treatment of functional constipation in children (fragment of the Draft clinical guidelines for the diagnosis and treatment of functional diseases of the digestive system in children developed by the Russian Society of Pediatric Gastroenterologists, Hepatologists and Nutritionists). 2020;(2): 60-68. (in Russ.) doi: 10.18565/pharmateca.2020.2.60-68.@@ Хавкин А. И., Файзуллина Р. А., Бельмер С. В. и др. Диагностика и лечение функциональных запоров у детей (фрагмент Проекта клинических рекомендаций по диагностике и лечению функциональных заболеваний органов пищеварения у детей Российского общества детских гастроэнтерологов, гепатологов и нутрициологов)- Фарматека. 2020-№ 2. C. 60-68. doi: 10.18565/pharmateca.2020.2.60-68.
15. O’Riordan K.J., Collins M. K., Moloney G. M. et al. Short chain fatty acids: Microbial metabolites for gut-brain axis signalling. Mol Cell Endocrinol. 2022 Apr 15;546:111572. doi: 10.1016/j.mce.2022.111572.
16. Góralczyk-Bińkowska A., Szmajda-Krygier D., Kozłowska E. The Microbiota-Gut-Brain Axis in Psychiatric Disorders.Int J Mol Sci. 2022 Sep 24;23(19):11245. doi: 10.3390/ijms231911245.
17. Molina-Torres G., Rodriguez-Arrastia M., Roman P., Sanchez-Labraca N., Cardona D. Stress and the gut microbiota-brain axis. Behav Pharmacol. 2019 Apr;30(2 and 3-Spec Issue):187-200. doi: 10.1097/FBP.0000000000000478.
18. Shrayner E. V., Kokh N. V., Lifshits G. I. Association of environmental factors with overweight and obesity in preschool and primary school children. The Siberian Journal of Clinical and Experimental Medicine. 2021;36(3):148-153. (In Russ.) doi: 10.29001/2073-8552-2021-36-3-148-153.@@ Шрайнер Е. В., Кох Н. В., Лифшиц Г. И. Ассоциация средовых факторов с избыточной массой тела и ожирением у детей дошкольного и младшего школьного возраста. Сибирский журнал клинической и экспериментальной медицины. 2021;36(3):148-153. doi: 10.29001/2073-8552-2021-36-3-148-153.
Review
For citations:
Shreiner E.V., Balakireva E.A., Bystrova V.I., Kovaleva A.Ya., Khavkin A.I. Stress in childhood: clinical implications and therapeutic strategies. Archives of Pediatrics and Pediatric Surgery. 2024;2(1):182-195. (In Russ.) https://doi.org/10.31146/2949-4664-apps-2-1-182-195
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