Experience of using a probiotic containing Lactobacillus reuteri B-9448 in children with acute infectious gastroenteritis
https://doi.org/10.31146/2949-4664-apps-2-1-104-112
Abstract
The article presents literature data on the relationship of disorders of the gastrointestinal tract with its microbiota in acute intestinal infections, as well as information on various beneficial properties of the probiotic microorganism Lactobacillus reuteri, including antagonistic effects on pathogenic and opportunistic pathogens, anti-inflammatory and immunomodulatory effects. The clinical and laboratory effectiveness of the use of a probiotic containing the Lactobacillus reuteri B-9448 strain in children with acute infectious gastroenteritis hospitalized. It was found that patients who received this probiotic in complex therapy spent significantly fewer bed days in the hospital compared to children who were not prescribed probiotic. At the same time, no undesirable side effects were registered in the group of patients treated with Lactobacillus reuteri B-9448, which indicates its safety.
About the Authors
S. G. Gorbunov
Research Clinical Institute of Childhood of the Moscow Region; “Russian Medical Academy of Continuous Professional Education” of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
N. V. Gonchar
Children’s Research and Clinical Centre for Infectious Diseases, Federal Medical and Biological Agency of Russia; North-Western State Medical University named after I. I. Mechnikov
Russian Federation
Russian Federation
A. V. Bitsueva
Research Clinical Institute of Childhood of the Moscow Region; Krasnogorsk City Hospital № 2 of the Ministry of Healthcare of the Moscow region
Russian Federation
Russian Federation
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Review
For citations:
Gorbunov S.G., Gonchar N.V., Bitsueva A.V. Experience of using a probiotic containing Lactobacillus reuteri B-9448 in children with acute infectious gastroenteritis. Archives of Pediatrics and Pediatric Surgery. 2024;2(1):104-112. (In Russ.) https://doi.org/10.31146/2949-4664-apps-2-1-104-112
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