The influence of epigenetic factors on the formation of health of newborns
https://doi.org/10.31146/2949-4664-apps-2-3-21-26
Abstract
The review is devoted to the study of the relationship of epigenetic factors with physiological and pathological processes in the development of the body of a newborn child. Modern aspects of the formation of microbiota and immunity, starting with fetal development, and the role of maternal lactobacilli in reproductive physiology are discussed. The effect of vaginal microbiota transfer on the development of the nervous system and the microbiome of newborns born by caesarean section. The characteristic of the formation of an immune response through Toll-like receptors is given. Breast milk as a biological system providing optimal physical and neuropsychiatric development, prevention of infectious and non-communicable diseases. The role of antibacterial therapy used in the antenatal period and in the first hours of life in the formation of late infections of newborns and disruption of their development is presented.
About the Authors
N. I. Zakharova
Research Clinical Institute of Childhood of the Ministry of Health of the Moscow Region
Russian Federation
Russian Federation
S. N. Lavrentyev
Research Clinical Institute of Childhood of the Ministry of Health of the Moscow Region; Moscow regional perinatal center of the Ministry of Health of the Moscow region
Russian Federation
Russian Federation
D. V. Aksenov
Research Clinical Institute of Childhood of the Ministry of Health of the Moscow Region
Russian Federation
Russian Federation
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Review
For citations:
Zakharova N.I., Lavrentyev S.N., Aksenov D.V. The influence of epigenetic factors on the formation of health of newborns. Archives of Pediatrics and Pediatric Surgery. 2024;2(3):21-26. (In Russ.) https://doi.org/10.31146/2949-4664-apps-2-3-21-26
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